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Impaired glucose tolerance and predisposition to the fasted state in liver glycogen synthase knock-out mice

PMID: 91 WangJLiHWangXShiRHuJZengXet al

Moreover, in addition to showing the direct inhibition of GAPDH by oxidation, the authors demonstrated that its activity is further hindered by DHA-induced NAD + depletion, since GAPDH activity relies on the availability of NAD + as a co-substrate

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